ea0021p280 | Pituitary | SFEBES2009
Higham Claire E
, Emy Phillipe
, Ferone Diego
, Finke Reinhard
, Laurberg Peter
, Main Katharina
, Maffei P
, Martini C
, Minuto Francesco
, Rainegard Isabelle
, Salzgeber Kirsten
, Vogel C
, Koltowska-Haggstrom Maria
, Trainer Peter J
Gigantism is an extremely rare condition and hence the relevant literature is largely a series of case reports. We present data on patients with gigantism <20 years of age identified from Pfizers Acrostudy registry of patients treated with pegvisomant.Eleven patients (5M) were identified: IGF1 at diagnosis was 1.6×ULN (1.153.3), height +5 SDS (1.13.8) and age 14.5 years (419). The three youngest (4, 7 and 14 years) had pi...